According to Bloomberg, Google has decided to eliminate all mosquitoes worldwide. Sounds okay, except you wonder if the ability to just cancel an entire class of animals that took millions of years to evolve could have unintended consequences or fall into the wrong hands.
This article in New Atlas (which I don’t know anything about) reports on an ultrasound-based treatment for dementia and Alzheimer’s that has been successful in mice and is moving to human trials next year.
The ultrasound treatment was first developed back in 2015 at the University of Queensland. The initial research was working to find a way to use ultrasound to temporarily open the blood-brain barrier with the goal of helping dementia-battling antibodies better reach their target in the brain. However, early experiments with mice surprisingly revealed the targeted ultrasound waves worked to clear toxic amyloid protein plaques from the brain without any additional therapeutic drugs.
“The ultrasound waves oscillate tremendously quickly, activating microglial cells that digest and remove the amyloid plaques that destroy brain synapses,” explained Jürgen Götz, one of the researchers on the project back in 2015. “The word ‘breakthrough’ is often mis-used, but in this case I think this really does fundamentally change our understanding of how to treat this disease, and I foresee a great future for this approach.”
Actually, on this site I am still allowed to say fuck, as far as I know. Why is it hard to type that in the title though? I would probably get more hits. Apologies to any parents out there whose children stumbled across this post. Then again, you should be sheltering them from mind-warping casual violence in entertainment, providing age-appropriate sex education, and teaching them the judicious, appropriate, and occasionally humorous uses of four letter words.
Anyway, this made me laugh. And while it is clearly satire, it is the least fake news I have read today.
Welcome to America General Hospital! Seems you have an oozing head injury there. Let’s check your insurance. Okay, quick “heads up” — ha! — that your plan may not cover everything today. What’s that? You want a reasonable price quote, upfront, for our services? Sorry, let me explain a hospital to you: we give you medical care, then we charge whatever the hell we want for it.
If you don’t like that, go fuck yourself and die…
Fun story: This one time we charged two parents $18,000 for some baby formula. LOL! We pull that shit all the time. Don’t like it? Don’t bring a baby, asshole.
Ha ha. It’s funny ’cause it’s true and it happens to all of us all the time, and we don’t do anything about it.
Most frightening and/or depressing stories:
Most hopeful stories:
Most interesting stories, that were not particularly frightening or hopeful, or perhaps were a mixture of both:
In case you were looking for something new to worry about today, this article in Wired says common sexually transmitted diseases like gonorrhea have become increasingly antibiotic resistant, and public funding for their treatment is at an all-time low.
I haven’t always been on the “organic” band wagon 100%. For one thing, the name is stupid. Chugging a glass of diesel fuel would be about as organic as you could get, in terms of the definition of the word I learned in high school chemistry. I am strongly in favor of sustainable farming practices that build soil, protect biodiversity, and prevent groundwater and surface water pollution. But in terms of health benefits, I have never felt the benefits were all that proven, and to some extent the industry is just based on scare tactics. I also wonder if the billions of humans on the planet can be fed without resorting to fossil fuel-derived fertilizer, and I still think that is dubious. But here is one large study in JAMA that did find significant evidence of a link between organic food (as labeled at the grocery store) and reduced cancer risk.
Association of Frequency of Organic Food Consumption With Cancer Risk: Findings From the NutriNet-Santé Prospective Cohort Study
Main Outcomes and Measures This study estimated the risk of cancer in association with the organic food score (modeled as quartiles) using Cox proportional hazards regression models adjusted for potential cancer risk factors.
Results Among 68 946 participants (78.0% female; mean [SD] age at baseline, 44.2 [14.5] years), 1340 first incident cancer cases were identified during follow-up, with the most prevalent being 459 breast cancers, 180 prostate cancers, 135 skin cancers, 99 colorectal cancers, 47 non-Hodgkin lymphomas, and 15 other lymphomas. High organic food scores were inversely associated with the overall risk of cancer (hazard ratio for quartile 4 vs quartile 1, 0.75; 95% CI, 0.63-0.88; P for trend = .001; absolute risk reduction, 0.6%; hazard ratio for a 5-point increase, 0.92; 95% CI, 0.88-0.96).
Conclusions and Relevance A higher frequency of organic food consumption was associated with a reduced risk of cancer. Although the study findings need to be confirmed, promoting organic food consumption in the general population could be a promising preventive strategy against cancer.
I researched the risk measures a little. The hazard risk ratio of 0.75 means that people eating mostly organic food (scoring in the top 25% of however they are measuring that) are 25% less likely than people eating the least organic food. That seems significant. From a quick skim, it appears they did try to control for differences in lifestyle (i.e., similar nutrition and exercise levels) and family history of cancer when coming to their conclusions.
Apparently, you can influence your circadian rhythm by heating up or cooling down your body at certain times of day, and a well-timed and designed bath is one way to do that. You’ll need a clock, a water thermometer, an air thermometer, and an understanding of the metric system.
In the study, researchers at the University of Freiburg in Germany assigned 45 people with depression to either soak in 40C water for up to 30 minutes and then wrap themselves in blankets and hot water bottles for a further 20 minutes, or take 40 to 45 minutes of aerobic exercise twice a week. Eight weeks later, those taking regular warm baths in the afternoon scored six points lower on a commonly used depression scale, while the exercise group scored three points lower on average…
Your bathwater should be just a little hotter than body temperature, which is about 37C. Somewhere between 40C and 45C is ideal…
Consider the temperature of the room as well. A Japanese study showed that bathing in 41C water in a 25C room increased body temperature more than taking a bath in a 14C room. However, if taking a bath to promote sleep before bed, the room temperature should be cooler: 18C is ideal.
This BBC article talks about how some people are using amphetamines like Adderall and Ritalin to stay focused and motivated in high pressure jobs. It clearly works, at least for short periods of time. It is not clear whether it can work longer term, because people may either need a significant recovery period to recover from use of the drugs, during which they are less focused and motivated than normal, or else they may become addicted to the drugs. But the article also points out that the new drugs are not qualitatively different from using coffee to stay focused and productive – it is just a matter of differences in degree and chemistry, and coffee has proven to be safe and even beneficial to most people.
Gene editing is starting to move into food, using CRISPR and something new (to me) called TALENs.
Calyxt’s soybean is the first of 23 gene-edited crops the Agriculture Department has recognized to date.
Scientists at Calyxt, a subsidiary of the French pharmaceutical firm Cellectis, developed their soybean by turning “off” the genes responsible for the trans fats in soybean oil. Compared with the conventional version, Calyxt says, oil made from this soybean boasts far more “healthy” fats, and far less of the fats that raise bad cholesterol…
Tripodi likes to say the product is akin to olive oil but without the pungent flavor that would make it off-putting in Oreos or granola bars. It has earned praise from the Center for Science in the Public Interest, a consumer group that says public health will benefit from ingredients with less trans and saturated fats, regardless of how they were developed.
I’m not really afraid of genetically engineered food, but when we monkey with whole foods in this way, it almost never ends up being healthier. Two good cases in point are vitamin pills and baby formula. If you want to be healthy, you should eat the actual soybeans rather than the Oreos or granola bars with soybean oil in them, whether genetically modified or not. And I happen to like olive oil, by the way.
My other concern is biodiversity. The more patented, altered, and homogeneous our food supply is, I wonder if it is more vulnerable to some pest or disease coming out of left field and wiping out the vast majority of it. This concern is not limited to genetic engineering either.
Just in case you are looking for something new to worry about, there is a gross new tick in the U.S. that can carry disease, swarm onto baby animals and suck all their blood out.