Tag Archives: longevity

September 2018 in Review

Most frightening stories:

Most hopeful stories:

  • The Suzuki and Kodaly methods are two ways of teaching music to young children that may actually help them think later in life. Training in jazz improvisation may also be good for young brains in a slightly different way.
  • There are some bright ideas for trying to improve construction productivity, which has languished for decades. Most involve some form of offsite fabrication.
  • In energy news, there’s a big idea to produce half the world’s electricity from sunlight in the Sahara desert. Another idea for collecting solar energy in otherwise (ecologically) wasted space is solar roadways, and there are a few prototypes around the world but this doesn’t seem to be a magic bullet so far. Another big idea is long-term storage of energy to smooth out fluctuations in supply and demand over months or even years.

Most interesting stories, that were not particularly frightening or hopeful, or perhaps were a mixture of both:

the old sucking the blood of the young?

There is grisly research where a young mouse is sown together with an old mouse and their blood vessels are connected. This seems to benefit the old mouse. And no, I haven’t watched “human centipede” and I have no desire to, although I did find the South Park parody of it moderately funny.

Beyond the stupidity of human centipede, you can imagine a mad dictator or Bond villain somewhere forcing people to be blood donors against their will. A more benign version would have biotech firms trying to synthesize whatever it is that makes young blood good, or possibly using stem cells to make a young version of a person’s blood. What if a version of me could be created that was just a bag of meat with no nervous system, and pumped out blood that kept me alive? That seems creepy but not necessarily unethical. Add a brain and keep that person sedated or otherwise detained against their will, and that would clearly be unethical (not to mention basically the plot of The Island.)

July 2018 in Review

Most frightening stories:

  • The UN is warning as many as 10 million people in Yemen could face starvation by the end of 2018 due to the military action by Saudi Arabia and the U.S. The U.S. military is involved in combat in at least 8 African countries. And Trump apparently wants to invade Venezuela.
  • The Trump administration is attacking regulations that protect Americans from air pollution and that help ensure our fisheries are sustainable. Earth Overshoot Day is on August 1 this year, two days earlier than last year.
  • The U.S. has not managed a full year of 3% GDP growth since 2005, due to slowing growth and the working age population and slowing productivity growth, and these trends seem likely to continue even if the current dumb policies that make them worse were to be reversed. Some economists think a U.S. withdrawal from the World Trade Organization could trigger a recession (others do not).

Most hopeful stories:

  • Looking at basic economic and health data over about a 50-200 time frame reminds us that enormous progress has been made, even though the last 20 years or so seems like a reversal.
  • Simultaneous Policy is an idea where multiple legislatures around the world agree to a single policy on a fairly narrow issue (like climate change or arms reductions).
  • I was heartened by the compassion Americans showed for children trapped in a cave 10,000 miles away. The news coverage did a lot to humanize these children, and it would be nice to see more of that closer to home.

Most interesting stories, that were not particularly frightening or hopeful, or perhaps were a mixture of both:

June 2018 in Review

Most frightening stories:

Most hopeful stories:

Most interesting stories, that were not particularly frightening or hopeful, or perhaps were a mixture of both:

  • Explicit taxes to fund wars were the norm in the U.S. right up to the Vietnam war.
  • In technology news, Google and Airbus are considering teaming to build a space catapult. The Hyperloop might be a real thing between Chicago’s downtown and airport.
  • Just under 0.1% of migrants crossing the U.S. border are members of criminal gang such as MS-13. About half of border crossers are from Mexico while the other half are mostly from Honduras, Guatemala, and El Salvador. Some are fleeing violence or repression, while others are simply looking for economic opportunity.

life expectancy in ancient societies

This article says life expectancy in ancient societies may not be as low as people tend to think. Many people are probably aware that child mortality brings down the average, but something I never thought about is how hard it is to measure the upper limit for populations that existed before any type of written records. There are people who specialize in digging up graves and doing exactly this, which seems a bit macabre.

We are all able to instinctively label people as ‘young’, ‘middle-aged’ or ‘old’ based on appearance and the situations in which we encounter them. Similarly, biological anthropologists use the skeleton rather than, say, hair and wrinkles. We term this ‘biological age’ as our judgment is based on the physical (and mental) conditions that we see before us, which relate to the biological realities of that person. These will not always correlate with an accurate calendar age, as people are all, well, different. Their appearance and abilities will be related to their genetics, lifestyle, health, attitudes, activity, diet, wealth and a multitude of other factors. These differences will accumulate as the years increase, meaning that once a person reaches the age of about 40 or 50, the differences are too great to allow any one-size-fits-all accuracy in the determination of the calendar age, whether it is done by eye on a living person or by the peer-preferred method of skeletal ageing. The result of this is that those older than middle age are frequently given an open-ended age estimation, like 40+ or 50+ years, meaning that they could be anywhere between forty and a hundred and four, or thereabouts.

The very term ‘average age at death’ also contributes to the myth. High infant mortality brings down the average at one end of the age spectrum, and open-ended categories such as ‘40+’ or ‘50+ years’ keep it low at the other. We know that in 2015 the average life expectancy at birth ranged from 50 years in Sierra Leone to 84 years in Japan, and these differences are related to early deaths rather than differences in total lifespan. A better method of estimating lifespan is to look at life expectancy only at adulthood, which takes infant mortality out of the equation; however, the inability to estimate age beyond about 50 years still keeps the average lower than it should be.

Archaeologists’ age estimates, therefore, have been squeezed at both ends of the age spectrum, with the result that individuals who have lived their full lifespan are rendered ‘invisible’. This means that we have been unable to fully understand societies in the distant past. In the literate past, functioning older individuals were mostly not treated much differently from the general adult population, but without archaeological identification of the invisible elderly, we cannot say whether this was the case in non-literate societies.

China passes U.S. in healthy life expectancy

  1. U.S. citizens still live a bit longer than Chinese citizens on average, but Chinese citizens have drawn even and slightly surpassed us in health.

https://www.axios.com/chinese-people-now-healthy-longer-than-americans-6dc7235f-e057-45ee-a975-c433611edabf.html

This would be perfectly fine if it just represented China catching up, but I suspect it represents the U.S. stalling as both our peers and developing countries continue to progress.

brain uploading

Good news – instead of killing you, slicing up your brain, freezing it and keeping it on ice so they can revive your consciousness centuries in the future, scientists might now be able to scan your brain and just store the pattern for later use. The bad news – they still have to kill you, slice up your brain, and freeze it first before they do the scanning. And of course there is still the old Star Trek transporter problem – when they save your pattern, disintegrate your matter, and recreate the pattern somewhere else using new matter, is it really still the same you, or is it a different you with the same memories as the original you? The new you won’t know the difference, and you won’t know the difference either because you won’t exist, so does it matter? Well, the technology still has a ways to go before we really have to worry about any of this. If they can ever find a way to save a detailed copy of your brain without killing you first, there would be very little downside to trying it. And before you ask, yes, I have read the book Altered Carbon, and no, I have not seen the new show Altered Carbon.

February 2018 in Review

Most frightening stories:

  • A general rule across many types of wildlife is that their range after urbanization decreases to between one-half and one-third of what it was before urbanization.
  • The Cuban sonic attacks are real. At least, the people who experienced them have real brain damage, even if we still don’t know what technology did the damage.
  • Cape Town will probably not be the last major city to run out of water.

Most hopeful stories:

Most interesting stories, that were not particularly frightening or hopeful, or perhaps were a mixture of both:

precision nutrition

Lancet has an article on precision nutrition and diabetes. Precision nutrition is the idea of a diet tailored specifically to an individual based on analysis of factors such as their genetics, proteins, and gut bacteria.

Precision nutrition for prevention and management of type 2 diabetes

Precision nutrition aims to prevent and manage chronic diseases by tailoring dietary interventions or recommendations to one or a combination of an individual’s genetic background, metabolic profile, and environmental exposures. Recent advances in genomics, metabolomics, and gut microbiome technologies have offered opportunities as well as challenges in the use of precision nutrition to prevent and manage type 2 diabetes. Nutrigenomics studies have identified genetic variants that influence intake and metabolism of specific nutrients and predict individuals’ variability in response to dietary interventions. Metabolomics has revealed metabolomic fingerprints of food and nutrient consumption and uncovered new metabolic pathways that are potentially modified by diet. Dietary interventions have been successful in altering abundance, composition, and activity of gut microbiota that are relevant for food metabolism and glycaemic control. In addition, mobile apps and wearable devices facilitate real-time assessment of dietary intake and provide feedback which can improve glycaemic control and diabetes management. By integrating these technologies with big data analytics, precision nutrition has the potential to provide personalised nutrition guidance for more effective prevention and management of type 2 diabetes. Despite these technological advances, much research is needed before precision nutrition can be widely used in clinical and public health settings. Currently, the field of precision nutrition faces challenges including a lack of robust and reproducible results, the high cost of omics technologies, and methodological issues in study design as well as high-dimensional data analyses and interpretation. Evidence is needed to support the efficacy, cost-effectiveness, and additional benefits of precision nutrition beyond traditional nutrition intervention approaches. Therefore, we should manage unrealistically high expectations and balance the emerging field of precision nutrition with public health nutrition strategies to improve diet quality and prevent type 2 diabetes and its complications.

I don’t want to be cynical, but I can imagine a scenario where this technology really catches on, but is accessible only to the rich. The result would be the rich living much longer than the rest of us (and they already live longer).